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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP1
All Species:
29.39
Human Site:
S313
Identified Species:
46.19
UniProt:
P61764
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61764
NP_001027392.1
594
67569
S313
S
L
K
D
F
S
S
S
K
R
M
N
T
G
E
Chimpanzee
Pan troglodytes
XP_001152683
595
67000
E314
E
L
L
R
T
F
C
E
S
K
R
L
T
T
D
Rhesus Macaque
Macaca mulatta
XP_001095617
580
66142
S299
S
L
K
D
F
S
S
S
K
R
M
N
T
G
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64324
593
66339
E312
E
L
L
K
T
F
C
E
S
K
R
L
T
T
D
Rat
Rattus norvegicus
P61765
594
67550
S313
S
L
K
D
F
S
S
S
K
R
M
N
T
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508183
589
67400
S299
S
L
K
D
F
S
S
S
K
R
M
N
T
G
E
Chicken
Gallus gallus
Q6R748
594
67454
S313
S
L
K
E
F
S
S
S
K
R
M
N
T
G
D
Frog
Xenopus laevis
NP_001093335
595
67691
K314
L
K
D
F
S
A
S
K
R
M
N
T
G
D
K
Zebra Danio
Brachydanio rerio
NP_001020353
591
67111
S313
S
L
K
E
F
S
A
S
K
R
M
N
T
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07327
597
67832
S322
N
L
K
K
F
T
D
S
K
R
M
G
S
A
D
Honey Bee
Apis mellifera
XP_396375
585
66573
S310
N
L
K
K
F
T
E
S
K
R
M
P
Q
G
D
Nematode Worm
Caenorhab. elegans
P34815
673
76715
K394
L
K
K
F
S
E
S
K
G
N
K
G
T
M
D
Sea Urchin
Strong. purpuratus
NP_999834
593
68046
K310
F
K
D
F
A
Q
G
K
K
M
G
S
G
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZ77
662
75299
K347
K
N
K
A
A
Q
L
K
H
S
S
K
D
F
G
Baker's Yeast
Sacchar. cerevisiae
P30619
724
83462
L338
E
L
I
A
K
N
P
L
L
V
D
R
S
N
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.8
97.6
N.A.
N.A.
62.7
100
N.A.
93.4
97.9
92.4
86.5
N.A.
63.4
63.9
52.1
60.9
Protein Similarity:
100
81.1
97.6
N.A.
N.A.
80.6
100
N.A.
96.1
99.4
97.9
94.6
N.A.
78
79.6
67.4
77.7
P-Site Identity:
100
13.3
100
N.A.
N.A.
13.3
100
N.A.
100
86.6
6.6
86.6
N.A.
46.6
53.3
20
13.3
P-Site Similarity:
100
26.6
100
N.A.
N.A.
26.6
100
N.A.
100
100
26.6
100
N.A.
73.3
73.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.2
22.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.2
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
14
14
7
7
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
14
27
0
0
7
0
0
0
7
0
7
7
47
% D
% Glu:
20
0
0
14
0
7
7
14
0
0
0
0
0
0
34
% E
% Phe:
7
0
0
20
54
14
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
0
0
7
0
7
0
7
14
14
54
7
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
20
67
20
7
0
0
27
60
14
7
7
0
0
7
% K
% Leu:
14
74
14
0
0
0
7
7
7
0
0
14
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
14
54
0
0
7
0
% M
% Asn:
14
7
0
0
0
7
0
0
0
7
7
40
0
7
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
14
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
7
54
14
7
0
0
0
% R
% Ser:
40
0
0
0
14
40
47
54
14
7
7
7
14
0
0
% S
% Thr:
0
0
0
0
14
14
0
0
0
0
0
7
60
14
0
% T
% Val:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _